KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL2C
All Species:
18.48
Human Site:
S416
Identified Species:
50.83
UniProt:
Q8IUH8
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IUH8
NP_787078.1
684
74503
S416
L
G
P
A
E
S
S
S
H
E
R
L
P
M
V
Chimpanzee
Pan troglodytes
XP_523673
684
74537
S416
L
G
P
A
D
S
S
S
H
E
R
L
P
M
V
Rhesus Macaque
Macaca mulatta
XP_001115879
684
74573
S416
S
G
P
A
E
S
S
S
H
E
K
L
P
M
V
Dog
Lupus familis
XP_548046
660
70155
S397
S
G
P
V
D
S
S
S
H
E
R
L
P
M
V
Cat
Felis silvestris
Mouse
Mus musculus
A2A6C4
690
76248
S425
S
G
P
A
D
S
S
S
H
E
R
L
P
M
V
Rat
Rattus norvegicus
Q5PQL3
577
63718
C326
D
T
L
G
I
A
F
C
L
Y
M
L
R
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507224
648
71872
C392
M
F
S
A
Q
T
L
C
V
I
P
F
S
L
L
Chicken
Gallus gallus
Q5F383
596
66378
T345
L
P
T
F
K
G
C
T
L
L
L
L
V
L
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782326
512
56836
A261
P
V
V
Y
V
V
I
A
L
Y
C
M
G
A
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.4
70.4
N.A.
69.1
41.5
N.A.
33
45.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Protein Similarity:
100
99.1
96.1
78.3
N.A.
80.2
57.5
N.A.
51
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
47.5
P-Site Identity:
100
93.3
86.6
80
N.A.
86.6
6.6
N.A.
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
86.6
N.A.
93.3
20
N.A.
40
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
56
0
12
0
12
0
0
0
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
12
23
0
0
12
0
0
0
0
% C
% Asp:
12
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
23
0
0
0
0
56
0
0
0
0
0
% E
% Phe:
0
12
0
12
0
0
12
0
0
0
0
12
0
0
12
% F
% Gly:
0
56
0
12
0
12
0
0
0
0
0
0
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
56
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
12
0
0
12
0
0
0
0
12
% I
% Lys:
0
0
0
0
12
0
0
0
0
0
12
0
0
0
0
% K
% Leu:
34
0
12
0
0
0
12
0
34
12
12
78
0
23
12
% L
% Met:
12
0
0
0
0
0
0
0
0
0
12
12
0
56
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
12
56
0
0
0
0
0
0
0
12
0
56
0
0
% P
% Gln:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
45
0
12
0
0
% R
% Ser:
34
0
12
0
0
56
56
56
0
0
0
0
12
0
0
% S
% Thr:
0
12
12
0
0
12
0
12
0
0
0
0
0
12
0
% T
% Val:
0
12
12
12
12
12
0
0
12
0
0
0
12
0
56
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% W
% Tyr:
0
0
0
12
0
0
0
0
0
23
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _